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About 444 Numbing Serum

444 Numbing Serum is a clinical-grade topical anesthetic engineered for pain relief. Built around a 4% lidocaine active, the serum delivers fast, reliable numbing — reaching onset in roughly 90 seconds and maximum efficacy within five minutes — while keeping swelling and redness to a minimum.

It was developed with one goal in mind: to make everyday life better and more pain-free. From the airtight, leak-proof packaging to the precision applicator tip, every detail is designed for consistent, dependable comfort whenever it's needed.

444/Serum

444 Numbing Serum — dermatological science created for your comfort.

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